Dr Claire Senner

B.Sc. (Imperial), M.Sc. (UCL), M.Res. (Imperial), Ph.D. (Imperial)

Postdoctoral Affiliate

College Roles

Postdoctoral Affiliate

Contact

Biography

Dr Claire Senner is a Next Generation Fellow at the Centre for Trophoblast Research where she studies molecular mechanisms underlying early development of the placenta. Claire carried out her PhD with Neil Brockdorff at Imperial College London. There she studied the regulation and function of the long non-coding RNA Xist, the master regulator of X chromosome inactivation, with a particular focus on imprinted X inactivation in the placental trophoblast lineage. She then joined Myriam Hemberger’s lab at the Babraham Institute, as a postdoc, where she characterised global DNA methylation dynamics in both embryo-derived and induced trophoblast stem cells.

Research Interests

Dr Claire Senner was awarded a Next Generation Fellowship in 2019 and is currently based in the Department of Physiology, Development and Neuroscience. In collaboration with Dr Erica Watson, she has been studying the impact of impaired one-carbon metabolism on epigenetic stability in the mouse placenta as well as initiating and leading her independent research into the role of the RNA processing and decay pathways in implantation and subsequent embryonic and placental development.